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Nitric oxide modulates the responses of osteoclast formation to static magnetic fields
文献类型:期刊
作者:Zhang, Jian[1]  Ding, Chong[2]  Meng, Xiaofeng[3]  Shang, Peng[4]  
机构:[1]Soochow Univ, Coll Med, Sch Radiat Med & Protect, Suzhou, Peoples R China.,Collaborat Innovat Ctr Radiat Med Jiangsu Higher, Suzhou, Peoples R China.;Northwestern Polytech Univ, Sch Life Sci, Key Lab Space Biosci & Biotechnol, Inst Special Environm Biophys, Xian, Shaanxi, Peoples R China.;
[2]Northwestern Polytech Univ, Sch Life Sci, Key Lab Space Biosci & Biotechnol, Inst Special Environm Biophys, Xian, Shaanxi, Peoples R China.;
[3]Northwestern Polytech Univ, Sch Life Sci, Key Lab Space Biosci & Biotechnol, Inst Special Environm Biophys, Xian, Shaanxi, Peoples R China.;
[4]Soochow Univ, Coll Med, Sch Radiat Med & Protect, Suzhou, Peoples R China.,Collaborat Innovat Ctr Radiat Med Jiangsu Higher, Suzhou, Peoples R China.;Northwestern Polytech Univ, Sch Life Sci, Key Lab Space Biosci & Biotechnol, Inst Special Environm Biophys, Xian, Shaanxi, Peoples R China.;
通讯作者:Shang, P (reprint author), Northwestern Polytech Univ, 127 Youyi Rd, Xian 710072, Shaanxi, Peoples R China.
年:2018
期刊名称:ELECTROMAGNETIC BIOLOGY AND MEDICINE影响因子和分区
卷:37
期:1
页码范围:23-34
增刊:正刊
收录情况:SCI(E)(WOS:000427940900003)  EI(20175104549957)  (29235883)  
所属部门:生命学院
人气指数:375
浏览次数:369
关键词:Static magnetic fields; osteoclast formation; nitric oxide; nitric oxide synthase
摘要:
Nitric oxide (NO) is involved in osteoclast differentiation. Our previous studies showed that static magnetic fields (SMFs) could affect osteoclast differentiation. The inhibitory effects of 16T of high SMF (HiMF) on osteoclast differentiation was correlated with increased production of NO. We raised the hypothesis that NO mediated the regulatory role of SMFs on osteoclast formation. In this study, 500nT of hypomagnetic field (HyMF), 0.2T of moderate SMF (MMF) and 16T of high SMF (HiMF) were uti ...More
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